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Carrascal MA, Silva M, Ferreira JA, Azevedo R, Ferreira D, Silva AMN, Ligeiro D, Santos LL, Sackstein R, Videira PA. A functional glycoproteomics approach identifies CD13 as a novel E-selectin ligand in breast cancer. Biochim Biophys Acta. 2018 May 17. pii: S0304-4165(18)30145-4. doi: 10.1016/j.bbagen.2018.05.013. [Epub ahead of print] PMID: 29777742

Carrascal MA, Talina C, Borralho P, Gonçalo Mineiro A, Henriques AR, Pen C, Martins M, Braga S, Sackstein R, Videira PA. Staining of E-selectin ligands on paraffin-embedded sections of tumor tissue. BMC Cancer. 2018 May 2;18(1):495. doi: 10.1186/s12885-018-4410-x. PMID: 29716546

Mondal N, Dykstra B, Lee J, Ashline DJ, Reinhold VN, Rossi DJ, Sackstein R. Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells. J Biol Chem. 2018 May 11;293(19):7300-7314. doi: 10.1074/jbc.RA117.000775. Epub 2018 Mar 28. PMID: 29593094

Silva M, Videira PA, Sackstein R. E-Selectin Ligands in the Human Mononuclear Phagocyte System: Implications for Infection, Inflammation, and Immunotherapy. Front Immunol. 2018 Jan 19;8:1878. doi: 10.3389/fimmu.2017.01878. eCollection 2017. Review. PMID: 29403469 Free PMC Article

Donnelly C, Dykstra B, Mondal N, Huang J, Kaskow BJ, Griffin R, Sackstein R, Baecher-Allan C. Optimizing human Treg immunotherapy by Treg subset selection and E-selectin ligand expression. Sci Rep. 2018 Jan 11;8(1):420. doi: 10.1038/s41598-017-17981-z. PMID: 29323143

Carrascal MA, Silva M, Ramalho JS, Pen C, Martins M, Pascoal C, Amaral C, Serrano I, Oliveira MJ, Sackstein R, Videira PA. Inhibition of fucosylation in human invasive ductal carcinoma reduces E-selectin ligand expression, cell proliferation, and ERK1/2 and p38 MAPK activation.Mol Oncol. 2018 May;12(5):579-593. doi: 10.1002/1878-0261.12163. Epub 2018 Mar 30. PMID: 29215790

Wu ZL, Person AD, Anderson M, Burroughs B, Tatge T, Khatri K, Zou Y, Wang L, Geders T, Zaia J, Sackstein R. Imaging specific cellular glycan structures using glycosyltransferases via click chemistry. Glycobiology. 2018 Feb 1;28(2):69-79. doi: 10.1093/glycob/cwx095. PMID: 29186441

Lee J, Dykstra B, Spencer JA, Kenney LL, Greiner DL, Shultz LD, Brehm MA, Lin CP, Sackstein R, Rossi DJ mRNA-mediated glycoengineering ameliorates deficient homing of human stem cell-derived hematopoietic progenitors. .J Clin Invest. 2017 Jun 1;127(6):2433-2437. doi: 10.1172/JCI92030. Epub 2017 May 8.PMID: 28481220Similar articles

Sackstein R, Schatton T, Barthel SR. T-lymphocyte homing: an underappreciated yet critical hurdle for successful cancer immunotherapy. Lab Invest. 2017 Jun;97(6):669-697. doi: 10.1038/labinvest.2017.25. Epub 2017 Mar 27. Review. PMID: 28346400

Silva M, Fung RKF, Donnelly CB, Videira PA, Sackstein R. Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology. J Immunol. 2017 May 1;198(9):3576-3587. doi: 10.4049/jimmunol.1601636. Epub 2017 Mar 22.PMID: 28330896

Pachón-Peña G, Donnelly C, Ruiz-Cañada C, Katz A, Fernández-Veledo S, Vendrell J, Sackstein R. A Glycovariant of Human CD44 is Characteristically Expressed on Human Mesenchymal Stem Cells. Stem Cells. 2017 Apr;35(4):1080-1092. doi: 10.1002/stem.2549. Epub 2017 Feb 5. PMID: 27888602

Buffone A Jr, Nasirikenari M, Manhardt CT, Lugade A, Bogner PN, Sackstein R, Thanavala Y, Neelamegham S, Lau JT. Leukocyte-borne α(1,3)-fucose is a negative regulator of β2-integrin-dependent recruitment in lung inflammation. J Leukoc Biol. 2017 Feb;101(2):459-470. doi: 10.1189/jlb.3A0516-215RR. Epub 2016 Aug 26. PMID: 27566832

Dykstra B, Lee J, Mortensen LJ, Yu H, Wu ZL, Lin CP, Rossi DJ, Sackstein R. Glycoengineering of E-Selectin Ligands by Intracellular versus Extracellular Fucosylation Differentially Affects Osteotropism of Human Mesenchymal Stem Cells. Stem Cells. 2016 Oct;34(10):2501-2511. doi: 10.1002/stem.2435. Epub 2016 Jul 17. PMID: 27335219

Sackstein R. Translational glycobiology: Patient-oriented glycoscience research. Glycobiology. 2016 Jun;26(6):544-5. doi: 10.1093/glycob/cww035. No abstract available. PMID: 27122387

Sackstein R. Fulfilling Koch's postulates in glycoscience: HCELL, GPS and translational glycobiology. Glycobiology. 2016 Jun;26(6):560-70. doi: 10.1093/glycob/cww026. Epub 2016 Feb 29. Review. PMID: 26933169

Agre P, Bertozzi C, Bissell M, Campbell KP, Cummings RD, Desai UR, Estes M, Flotte T, Fogleman G, Gage F, Ginsburg D, Gordon JI, Hart G, Hascall V, Kiessling L, Kornfeld S, Lowe J, Magnani J, Mahal LK, Medzhitov R, Roberts RJ, Sackstein R, Sarkar R, Schnaar R, Schwartz N, Varki A, Walt D, Weissman I. J Training the next generation of biomedical investigators in glycosciences. Clin Invest. 2016 Feb;126(2):405-8. doi: 10.1172/JCI85905. Epub 2016 Feb 1. Review. PMID: 26829621

Merzaban JS, Imitola J, Starossom SC, Zhu B, Wang Y, Lee J, Ali AJ, Olah M, Abuelela AF, Khoury SJ, Sackstein R. Cell surface glycan engineering of neural stem cells augments neurotropism and improves recovery in a murine model of multiple sclerosis. Glycobiology. 2015 Dec;25(12):1392-409. doi: 10.1093/glycob/cwv046. Epub 2015 Jul 7. PMID: 26153105

Lee J, Dykstra B, Sackstein R, Rossi DJ.  Progress and obstacles towards generating hematopoietic stem cells from pluripotent stem cells.  Current Opinion in Hematology, 2015; 22(4):317-23.  PMCID: PMC4459525.

Sackstein R, Fuhlbrigge R.  Western blot analysis of adhesive interactions under fluid shear conditions: the blot rolling assay.  Methods in Molecular Biology, 2015; 1312:399-410.

Abdi R, Moore R, Sakai S, Donnelly CB, Sackstein R.  HCELL expression on murine MSC Licenses Pancreatotropism and Confers Durable Reversal of Autoimmune Diabetes in NOD Mice.  Stem Cells. 2015; 33:1523-31.  PMCID: PMC4447299.

Silvescu C, Sackstein R. G-CSF induces membrane expression of a myeloperoxidase glycovariant that operates as an E-selectin ligand on human myeloid cells.  Proc. Natl. Acad. Sci. 2014; 111:10696-10701.  PMCID: PMC4115493.

Batal I, Azzi J, Mounayar M, Moore R, Lee JY, Rosetti F,  Wang C, Fiorina P, Sackstein R, Ichimura T, Abdi R.  The mechanisms of up-regulation of dendritic cell activity by oxidative stress.  J Leuk Biology 2014; 96:283-93.  PMCID: PMC4101089.

Dauber A, Ercan A, Lee J, James P, Jacobs PP, Ashline DJ, Wang SR, Miller T, Hirschhorn JN, Nigrovic PA, Sackstein R. Congenital Disorder of Fucosylation Type 2c (LADII) Presenting with Short Stature and Developmental Delay with Minimal Adhesion Defect. Hum Mol Genet 2014; 23:2880-87.  PMCID: 4014190.

Peter Y, Sen N, Keller S, Ingenito EP, Ciner A, Sackstein R, Shapiro SD. CD45/CD11b-positive subsets of adult lung anchorage-independent cells harness epithelial stem cells in culture. J Tissue Eng Regen Medicine 2013; 7:572-83. PMCID: PMC4434406.

Sackstein, R.  Re: Ex Vivo Fucosylation Improves Human Cord Blood Engraftment in NOD/SCID IL-2Rgnull Mice.  Experimental Hem.  2012, Published On-line, April 2012.

Sackstein R. Glycoengineering of HCELL, the Human Bone Marrow Homing Receptor: Sweetly Programming Cell Migration. Annals of Biomedical Engineering, 2012; 40:766-776.  PMCID: PMC3311703.

Sackstein, R. Engineering cellular trafficking via glycosyltransferase-programmed stereosubstitution.  Annals of New York Acad. Sci., 2012; 1253: 193-200.  PMCID: in process.

Jansen GAJ, Josefsson EC, Rumjantseva V, Liu QP, Falet H, Bergmier W, Cifuni SM, Sackstein R, von Andrian UH, Wagner DD, Hartwig JH, Hoffmeister K. Desialylation acclerates platelet clearance following refrigeration and initiates GPIba metalloproteinase-mediated cleavage in mice.  Blood 2012; 119:1263-73.  PMCID: PMC3277358.

Jacobs P, Sackstein R CD44 and HCELL: Preventing Hematogenous Metastasis at Step 1. FEBS Letters, 2011; 585:3148-3158. PMCID: PMC3195965.

Merzaban JS, Burdick M, Gadhoum SZ, Dagia NM, Chu1 JT, Fuhlbrigge RC, Sackstein R. Analysis of Glycoprotein E-selectin Ligands on Human and Mouse Marrow Cells Enriched for Hematopoietic Stem/Progenitor Cells. Blood 2011; 118:1774-1783. PMCID: PMC3158712

Sackstein R. The Biology of CD44 and HCELL in Hematopoiesis: The “Step 2-bypass Pathway” and other Emerging Perspectives. Current Opinion in Hematology, 2011; 18:239-48. PMCID: PMC3145154

Thankamony S, Sackstein R.  Enforced hematopoietic cell E- and L-selectin ligand (HCELL) expression primes transendothelial migration of human mesenchymal stem cells. Proc. Natl. Acad. Sci. 2011; 108: 2258-2263. PMCID: PMC3038774

Sackstein, R. Hitting the Sweet Spot for Lymphoma. Blood, 2010; 115: 4626-27.

Chester R, Sackstein R.  Embryonic Stem Cell-based Therapeutics: Balancing Scientific Progress and Bioethics. Health Matrix: The Journal of Law-Medicine. 2010; 20:1-15.

Sackstein, R. Directing Stem Cell Trafficking via GPS. Methods in Enzymology, 2010; 479: 93-105.

Lee J, Buzney C, Poznansky M, Sackstein R.   Dynamic alterations in chemokine gradients induce transendothelial shuttling of human T cells under physiologic shear conditions.  J. Leuk. Biology 2009; 86:1285-1294. PMCID: PMC2796626

Sackstein, R.  Glycosyltransferase-Programmed Stereosubstitution (GPS) to Create HCELL: Engineering a Roadmap for Cell Migration. Immunological Reviews, 2009; 230: 140-163.

Nigro J, Wang A, Mukhopadhyay D, Lauer ME, Midura RJ, Sackstein R, Hascall VC. Regulation of Heparan Sulfate and Chondroitin Sulfate Glycosylaminoglycan Biosynthesis by 4-fluoro-glucosamine in Murine Airway Smooth Muscle Cells. J. Biol. Chem. 2009; 284:16832-16839. PMCID: PMC2719319

Sackstein, R, Fuhlbrigge R.  Western Blot Analysis of Adhesive Interactions under Fluid Shear Conditions: The Blot Rolling Assay. In: Protein Blotting and Detection, Methods and Protocols (Kurien, Biji T.; Scofield, R. Hal, eds), Humana Press, Springer Science Media, New York, NY (Methods in Molecular Biology Series).  Methods Mol Biol. 2009; 536: 343-354.

Gadhoum SZ and Sackstein R. CD15/Lewis x Expression in Human Myeloid Cell Differentiation is Regulated by Sialidase Activity. Nature Chemical Biology 2008; 4:751-757. PMCID: PMC2597094

Ngo HT, Leleu X, Lee J, Melhem M, Jia X, Runnels J, Moreau A-S, Azab AK, Roccaro A, Azab F, Sacco A, Burwick N, Farag M, Kung AL, Lin CP, Sackstein R, Ghobrial IM. SDF-1/CXCR4 and VLA-4 Interaction Regulates Homing in Waldenstrom Macroglobulinemia.  Blood, 2008; 112:150-158. PMCID: PMC2435685

Resto V, Burdick MM, Dagia NM, McCammon SD, Fennewald SM, Sackstein R. L-selectin-mediated Lymphocyte-Cancer Cell Interactions under Low Fluid Shear Conditions. J. Biol. Chem. 2008; 283:15816-15824. PMCID: PMC2414279

Shaulov A, Yue S, Wang RJ, Joyce RM, Balk SP, Kim HT, Avignan DE, Uhl L, Sackstein R,  Exley MA. Peripheral Blood Progenitor Cell Product Contains Th1-biased Noninvariant CD1d-reactive Natural Killer T Cells: Implications for Posttransplant Survival. Experimental Hematology 2008; 36:464-472. PMCID: PMC2390922

Sackstein R, Merzaban JS, Cain DW, Dagia NM, Spencer JA, Lin CP, Wohlgemuth R.  Ex Vivo Glycan Engineering of CD44 Programs Human Multipotent Stromal Cell Trafficking to Bone. Nature Medicine 2008; 14:181-187.

Spitzer, T.R., Sackstein, R. Graft-versus-Host Disease: New Perspectives on Pathobiology and Treatment. In:  Clinical Malignant Hematology (M. Sekeres, M. Kalacyio, B. Bolwell, eds.), McGraw-Hill Publishers, N.Y., 2007, pp. 1051-1062.

Parmar K, Vergilio J, Mauch P, Sackstein R, Down JD.  Distribution of Hematopoietic Stem Cells in the Bone Marrow According to Regional Hypoxia.  Proc. Natl. Acad. Sci. USA. 2007; 104: 5431-5438. PMCID: PMC1838452.

Schreiber TS, Shinder V, Cain D, Alon R, Sackstein R. Shear flow-dependent Integration of Apical and Subendothelial Chemokines in T Cell Transmigration: Implications for Locomotion and the “Multi-step Paradigm”. Blood 2007; 109:1383-1388.  PMCID: PMC1794074.

Dagia NM, Gadhoum SZ, Knoblauch CA, Spencer JA, Zamiri P, Lin CP, Sackstein R. G-CSF Induces E-selectin Ligand Expression on Human Myeloid Cells.  Nature Medicine 2006; 12:1185-1190.

Burdick MM, Chu JT, Godar S, Sackstein RHCELL is the major E- and L-selectin ligand expressed on LS174T colon carcinoma cells. J. Biol. Chem. 2006; 281:13899-905.

Fuhlbrigge RC, King SL, Sackstein R, Kupper TS. CD43 is a Ligand for E-selectin on CLA+ Human T Cells. Blood 2006; 107:1421-1426.  PMCID: PMC1895405.

Hanley WD, Napier SL, Burdick MB, Schnaar RL, Sackstein R and Konstantopoulos K. Variant Isoforms of CD44 are P- and L-Selectin Ligands on Colon Carcinoma Cells. FASEB Journal 2006; 20:337-339.

Sackstein, R. A Revision of Billingham’s Tenets: The Central Role of Lymphocyte Migration in Acute Graft-versus-Host Disease.  Biology of Blood and Marrow Transplantation, 2006; 12:2-8.

Sackstein, R, Fuhlbrigge, RC. The Blot Rolling Assay: A Method for Identifying Adhesion Molecules Mediating Binding under Shear Flow.  In: Cell-Cell Interactions (S. Colgan, ed.), Humana Press, TotowaN.J., 2006, pp. 217-226.

Sackstein, R.  The Lymphocyte Homing Receptors: Gatekeepers of the Multistep Paradigm.  Current Opinion in Hematology, 2005, 12(6):444-450.

Hanley WD, Burdick MM, Konstantopoulos K and Sackstein R.  CD44 on LS174T Colon Carcinoma Cells Possesses E-selectin Ligand Activity.  Cancer Res. 2005; 65:5812-5817.

Dey BR, McAfee S, Colby C, Cieply K, Caron M, Saidman S, Preffer F, Shaffer J, Tarbell N, Sackstein R, Sachs D, Sykes M and Spitzer TR.  Anti-tumor Response Despite Loss of Donor Chimerism in Patients Treated with Nonmyeloablative Conditioning and Allogeneic Stem Cell Transplantation.  Br. J. Hematology 2005; 128:351-359.

Sackstein R.  The Bone Marrow is Akin to Skin: HCELL and the Biology of Hematopoietic Stem Cell Homing.  J. Invest. Dermatology, Symposium Proceedings, 2004, 9:215-223.

Sackstein R. The Bone Marrow is Akin to Skin: HCELL and the Biology of Hematopoietic Stem Cell Homing. J. Invest. Dermatology, 2004, 122:1061-1069.

Elfenbein GJ, Sackstein R.  Primed Marrow for Autologous and Allogeneic Transplantation: A New Perspective from Reviewing the Published Literature.  Exp. Hematology 2004; 32:327-339.

Milinkovic M, Antin JH, Hergrueter CA, Underhill CB, Sackstein R. CD44-Hyaluronic Acid Interactions Mediate Shear-resistant Binding of Lymphocytes to Dermal Endothelium in Acute GVHD. Blood 2004; 103: 740-742.

Elfenbein GJ, Sackstein R, Oblon DJ. Do G-CSF mobilized, peripheral blood-derived stem cells from healthy, HLA-identical donors really engraft more rapidly than do G-CSF primed, bone marrow-derived stem cells?  Blood Cells, Molecules and Diseases 2004; 32: 106-111.

Dey BR, Colby C, Sackstein R, Saidman S, Tarbell N, Sachs DH, Sykes M, Spitzer TR.  Impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor response in patients with advanced hematologic malignancies treated with a nonmyeloablative conditioning and allogeneic bone marrow transplantation. Blood and Marrow Transplantation Reviews, 2003, 13:10-12.

Dimitroff CJ, Kupper TS, Sackstein R.  Prevention of Leukocyte Migration to Inflamed Skin with a Novel Fluorosugar Modifier of Cutaneous Lymphocyte-Associated Antigen. Journal of Clinical Investigation 2003; 112:1008-1018. PMCID: PMC198531. 

Kraus AB, Shaffer J, Toh HC, Preffer F, Dombkowski D, Saidman S, Colby C, George R, McAfee S, Sackstein R, Dey B, Spitzer TR, Sykes M.  Early Host CD8 T-cell Recovery and Sensitized Anti-Donor IL-2-Producing and T Cell CTL Responses Associated with Marrow Graft Rejection Following Non-myeloablative Allogeneic Bone Marrow Transplantation.  Experimental Hematology 2003; 31:609-21.

Daly A, McAfee S, Dey B, Colby C, Schulte L, Yeap B, Sackstein R, Tarbell NJ, Sachs D, Sykes M, Spitzer TR.  Nonmyeloablative bone marrow transplantation: Infectious complications in 65 recipients of HLA-identical and mismatched transplants. Biol Blood Marrow Transplantation 2003; 9:373-82.

Dey BR, McAfee S, Colby C, Sackstein R, Saidman S, Tarbell N, Sachs DH, Sykes M, Spitzer TR.  The impact of prophylactic donor leukocyte infusions on mixed chimerism, graft-versus-host disease, and antitumor responses in patients with advanced hematologic malignancies treated with nonmyeloablative conditioning and allogeneic bone marrow transplantation.  Biol Blood Marrow Transplantation 2003; 9:320-329.

Dimitroff CJ, Bernacki RJ, Sackstein R.  Inhibition of Cutaneous Lymphocyte-Associated Antigen Expression: Implications in Modulating Lymphocyte Migration to Skin.  Blood 2003; 101:602-610.

Sackstein R, Messina J, Elfenbein GJ.  In Vitro Adherence of Lymphocytes to Dermal Endothelium Under Shear Stress: Implications in Pathobiology and Steroid Therapy of Acute Cutaneous Graft versus Host Disease.  Blood 2003; 101:771-778.

Toh HC, Spitzer TR, Preffer F, Alexander SI, McAfee S, Dombowski D, Clark JS, Colby C, Saidman S, Sackstein R, Sykes M.  Fluctuating Lymphocyte Chimerism, Tolerance and Anti-tumor Response in a Patient with Refractory Lymphoma Receiving Non-myeloablative Conditioning and a Haploidentical Related Allogeneic Bone Marrow Transplant.  Cytokines Cell Mol Ther.  2002; 7:43-47.

Buhler L, Spitzer TR, Sykes M, Sachs DH, Delmonico F, Rubin N, Saidman S, Sackstein R, McAfee S, Dey B, Colby C, Wemouth D, Cosimi AB.  Induction of Kidney Allograft Tolerance through Mixed Lymphohematopoietic Chimerism in Patients with Multiple Myeloma and End-stage Renal Disease.  Transplantation  2002; 74:1405-1409.

Buhler L, Kurilla-Mahon B, Chang Q, Abraham S, Alwayn IPJ, Appel JZ, Newman D, Awwad M, White-Scharf ME, Sackstein R, Sachs DH, Cooper DKC, Down JD.  Cryopreservation and Mycophenolate Therapy are Detrimental to Hematopoietic Progenitor Cells.  Transplantation 2002; 74:1159-1166.

Theodore PR, Simon AR, Warren AN, Sackstein R, Sykes M.  Porcine Mononuclear Cells Adhere to Human Fibronectin Independently of VLA-5:  Implications for Donor-specific Tolerance Induction in Xenotransplantation.  Xenotransplantation  2002; 9:277-89.

Fuhlbrigge R, King SL, Dimitroff CJ, Kupper TS, Sackstein R. Direct Real-time Observation of E- and P-selectin Mediated Rolling on Cutaneous Lymphocyte-Associated Antigen Immobilized on Western Blots.  J. Immunology 2002; 168: 5645-51.

Buhler L, Awwad M, Down JD, Treter S, Chang Q, Ericsson T, Harper D, Kurilla-Mahon B, Alwayn IPJ, Basker M, Huang C,Sackstein R, Sykes M, White-Scharf ME, Sachs DH, Cooper DKC.  Pig hematopoietic cell chimerism in baboons conditioned with a nonmyeloablative regimen and CD154 blockade.  Transplantation  2002; 73:12-22.

Spitzer TR, McAfee SL, Sackstein R, Colby C, Dey B, Saidman S, Preffer F, Sachs DH, Sykes M.  Mixed lymphohematopoietic chimerism and delayed donor leukocyte infusions following non-myeloablative conditioning and HLA-matched and mismatched donor bone marrow transplantation (BMT).  In: Autologous Bone Marrow Transplantation. (Dicke KA, Keating A, editors). Carden JenningsCharlottesvilleVA, 2001, pp. 321-330.

Dimitroff CJ, Lee JY, Schor KS, Sandmaier BM, Sackstein R.  Differential L-selectin Binding Activities of the Human Hematopoietic Cell L-selectin Ligands, HCELL and PSGL-1.  J. Biol. Chem.  (Published On-Line in October, 2001)  2001; 276:47623-631.

Exley M, Tahir SMA, Cheng O, Shaulov A, Wang R-J, Joyce R, Avigan D, Sackstein R, Balk SP.  A Major Fraction of Human Bone  Marrow Lymphocytes are Th2-Like CD1d-reactive T Cells that can Suppress Mixed Lymphocyte Reactions.  J. Immunology  2001; 167:5531-34.

Gonzalez S, Sackstein RAnderson RR, Rajadhyaksha M.  Real-time evidence of in vivo leukocyte trafficking in human skin by reflectance confocal microscopy.  Journal of Investigative Dermatology  2001; 117:384-386.

Alwayn IPJ, Buhler L, Appel JZ, Goepfert C, Csizmadia E, Correa L, Harper D, Kitamura H, Down JD, Awwad M,  Sackstein R, Cooper DKC, Robson SC.  Mechanisms of Thrombotic Microangiopathy Following Xenogeneic Hematopoietic Progenitor Cell Transplantation.  Transplantation  2001; 71:1601-1609.

Dimitroff CJ, Lee JY, Rafii S, Fuhlbrigge RC, Sackstein R.  CD44 is a Major E-selectin Ligand on Human Hematopoietic Progenitor Cells.  J. Cell Biology 2001; 153: 1277-1286.

Bühler L, Goepfert C, Kitamura H, Alwayn IPJ, Basker M, Gojo S, Chang Q, Down JD, Tsai HM,  Sachs DH, Cooper DKC, Robson SC, Sackstein R. Porcine hematopoietic cell xenotransplantation in non-human primates is complicated by thrombotic microangiopathy.  Bone Marrow Transplantation  2001; 27:1227-1236.

Dey BR, McAfee S, Sackstein R, Colby C, Saidman S, Weymouth D, Poliquin C, Vanderklish J, Sachs DH, Sykes M, Spitzer TR.  Successful Allogeneic Stem Cell Transplantation with Nonmyeloablative Conditioning in Patients with Relapsed Hematologic Malignancy Following Autologous Stem Cell Transplantation.  Biol. Blood Marrow Transplantation  2001; 7:604-12.

Alwayn IP, Buhler L, Basker M, Goepfert C, Kawai T, Kozlowski T, Ierino F, Sachs DH, Sackstein R, Robson SC, Cooper DK. Coagulation/thrombotic disorders associated with  organ and cell xenotransplantation. Transplant Proc. 2000, 32:1099.Gopfert C, Buhler L, Wise R, Basker M, Gojo S, Imai M, Alwayn I, Sachs DH, Sackstein R, Cooper DK, Robson SC. Von willebrand factor concentration, multimeric patterns, and cleaving protease activity in baboons undergoing xenogeneic peripheral blood stem cell transplantation. Transplant Proc. 2000, 32:990.

Dimitroff CJ, Lee J, Fuhlbrigge RC, Sackstein R.  A distinct glycoform of CD44 is an L- selectin ligand on human hematopoietic progenitor cells.  Proc. Natl. Acad. Sci. USA 2000; 97:13841-13846.

Buhler L, Basker M, Alwayn IPJ, Goepfert C, Kitamura H, Kawai T, Gojo S, Kozlowski T, Ierino FL, Awwad M, Sachs DH,Sackstein R, Robson SC, Cooper DKC.  Coagulation and thrombotic disorders associated with pig organ and hematopoietic cell transplantation in nonhuman primates. Transplantation 2000; 70:1323-1331.

Sackstein R, Dimitroff CJ.  An hematopoietic cell L-selectin ligand that is distinct from PSGL-1 and displays N-glycan-dependent binding activity.  Blood 2000; 96:2765-2774.

Buhler L, Awwad M, Basker M, Gojo S, Thall A, Down JD, Sykes M, Andrews D, Sackstein R, White-Scharf ME, Sachs DH, Cooper DK. A nonmyeloablative regimen with CD40L blockade leads to humoral and cellular hyporesponsiveness to pig hematopoietic cells in baboons. Transplant Proc. 2000, 32:1100.

Alwayn IP, Buhler L, Basker M, Goepfert C, Kawai T, Kozlowski T, Ierino F, Sachs DH, Sackstein R, Robson SC, Cooper DK. Coagulation/thrombotic disorders associated with  organ and cell xenotransplantation. Transplant Proc. 2000, 32:1099.

Gopfert C, Buhler L, Wise R, Basker M, Gojo S, Imai M, Alwayn I, Sachs DH, Sackstein R, Cooper DK, Robson SC. Von willebrand factor concentration, multimeric patterns, and cleaving protease activity in baboons undergoing xenogeneic peripheral blood stem cell transplantation. Transplant Proc. 2000, 32:990.

Buhler L, Awwad M, Basker M, Gojo S, Watts A, Treter S, Nash K, Oravec G, Chang Q, Thall A, Down J, Sykes M, Andrews D,  Sackstein R, White-Scharf M, Sachs DH, Cooper DKC.  High-dose porcine hematopoietic cell transplantation combined with CD40L blockade in baboons prevents an induced anti-pig humoral response.  Transplantation 2000; 69:2296-304.

Colby C, Chang Q, Fuchimoto Y, Ferrara V, Sackstein R, Spitzer TR, Scharf-White ME, Sachs DH. Cytokine-mobilized peripheral blood progenitor cells for allogeneic reconstitution of miniature swine. Transplantation  2000; 69:135-140.

Spitzer TR, McAfee S, Sackstein R, Colby C, Toh HC, Multani P, Saidman S, Weymouth D, Preffer F, Poliquin C, Foley A, Cox B, Dombowski D, Andrews D, Sachs DH, Sykes M.  The intentional induction of mixed chimerism and achievement of anti-tumor responses following non-myeloablative conditioning therapy and HLA-matched and mismatched donor bone marrow transplantation for refractory hematologic malignancies.  Biology of Blood and Marrow Transplantation 2000; 6:309-320.

Toh HC, McAfee SL, Sackstein R, Multani P, Cox BF, Garcia-Carbonero R, Colby C, Spitzer TR.  High-dose cyclophosphamide + carboplatin and interleukin-2 (IL-2) activated autologous stem cell transplantation followed by maintenance IL-2 therapy in metastatic breast carcinoma – A phase II study.  Bone Marrow Transplantation 2000; 25:19-24.

Janssen WE, Elfenbein GJ, Perkins JB, Partyka JF, Smiley RC, Ballester OF, Goldstein SC, Fields KK, Heimenz JW,Sackstein R, Zorsky PE. Final report of the first prospective, stratified, randomized trial comparing G-CSF primed bone marrow cells with G-CSF mobilized peripheral blood cells for pace of hematopoietic engraftment and disease free survival after high dose therapy and autotransplant.  In: Autologous Blood and Marrow Transplantation. (Dicke KA, Keating A, editors). Carden Jennings,CharlottesvilleVA, 1999, pp. 580-598.

Spitzer, T.R., Sackstein, R. Graft-versus-Host Disease: Has any progress been made in the past decade? In:  Bone Marrow Transplantation (B. Bolwell, ed.), Humana Press, TotowaN.J., 1999, pp. 229-248.

Salgia R, Quackenbush E, Lin J, Souchkova N, Sattler M, Ewaniuk DS, Klucher KM, Daley GQ, Kraeft SK, Sackstein R, Alyea EP, von Adrian UH, Chen LB, Gutierrez-Ramos J-C, Pendergast A-M, Griffin JD. The BCR/ABL oncogene alters the chemotactic response to Stromal-Derived Factor-1a.  Blood 1999; 94:4233-4246.

Colby C, McAfee SL, Sackstein R, Finkelstein DM, Fishman JA, Spitzer TR.  A prospective randomized trial comparing the toxicity and safety of atovaquone with trimethoprim/sulfamethoxazole as Pneumocystis carinii pneumonia prophylaxis following autologous peripheral blood stem cell transplantation.  Bone Marrow Transplantation 1999; 24: 897-902.

Toh HC, McAfee SL, Sackstein R, Cox BF, Colby C, Spitzer TR. Late-onset veno-occlusive disease following high dose chemotherapy and stem cell transplantation.  Bone Marrow Transplantation 1999; 24:891-895.

Spitzer TR, Delmonico F, Tolkoff-Rubin N, McAfee S, Sackstein R, Saidman S, Colby C, Sykes M, Sachs DH, Cosimi AB.  Combined HLA-matched donor bone marrow and renal transplantation for multiple myeloma with end stage renal disease: The induction of allograft tolerance through mixed lymphohematopoietic chimerism.  Transplantation 1999; 68: 480-484.

Sykes M, Preffer F, McAfee S, Saidman SL, Weymouth D, Andrews D, Colby C, Sackstein R, Sachs DH and Sykes M.  Mixed lymphohematopoietic chimerism and graft-vs-lymphoma effects after non-myeloablative therapy and HLA-mismatched donor bone marrow transplantation.  Lancet  1999; 353:1755-1759. 

Ballester OF, Tummala R, Janssen WE, Fields KK, Hiemenz JW, Goldstein SC, Perkins JB, Sullivan DM, Rosen R, Sackstein R, Zorsky P, Saez R, Elfenbein GJ.  High-dose chemotherapy and autologous peripheral blood stem cell transplantation in patients with multiple myeloma and renal insufficiency.  Bone Marrow Transplantation 1997, 20:653-656.

Sackstein R, Fu L, Allen KL.  A hematopoietic cell L-selectin ligand exhibits sulfate-independent binding activity.  Blood 1997; 89:2773-2781.

Sackstein R.  Expression of an L-selectin ligand on hematopoietic progenitor cells.  Acta Haematol. 1997, 97:22-28.

Sackstein R, Chao N.  Veno-occlusive disease of the liver following bone marrow transplantation.  In:  The kidney in liver disease, 4th Edition, (M. Epstein, Ed.), Hanley and Belfus, Philadelphia, 1996, pp. 167-178.

Wasik MA, Sackstein R, Novick D, Butmarc JR, Vonderheld E, Kadin MD.  Cutaneous CD56+ large (T-) cell lymphoma associated with a high concentration of circulating IL-2.  Human Pathology 1996; 27:738-744.

Sackstein R.  Disruption of lymphocyte homing to lymph nodes following bone marrow transplantation:  implications for immune reconstitution.  Clinical Immunology Newsletter 1995, 15:144-149.

Sackstein R, Janssen WE, Elfenbein GJ. (editors).  Bone marrow transplantation:  foundations for the 21st century (Proceedings of the New York Academy of Sciences Conference, March, 1995).  Ann. of NY Acad. Sci., Volume 770, 1995.

Sackstein R.  Lymphocyte migration following bone marrow transplantation.  Ann. of NY Acad Sci. 1995, 770:177-188.

Sackstein R.  The physiologic basis of steroid-induced immunosuppression:  effects on lymphocyte migration to lymph nodes.  J. Fla. Med. Assoc. 1995, 82:613-615.

Sackstein R, Meng, L, Xu XM, Chin YH.  Evidence of post-transcriptional regulation of L-selectin gene expression in rat lymphoid cells.  Immunology 1995; 85:198-204.

Sackstein R, Borenstein M.  The effects of corticosteroids on lymphocyte recirculation in humans: analysis of the mechanism of impaired lymphocyte migration to lymph node following methylprednisolone administration.  J. Invest. Med. 1995; 43:68-77.

Oxley SM, Sackstein R.  Detection of an L-selectin ligand on a hematopoietic progenitor cell line.  Blood 1994; 84:3299-3306.

Sackstein R.  Adoptive immunotherapy: the magic bullet of cancer therapy?  Cancer Control 1994, 1:64-68.

Sackstein R.  Effects of methylprednisolone administration on lymphocyte LECAM-1, CD44 and LFA-1 expression:  implications for steroid-induced lymphopenia.  Annals of NY Acad Sci.  1993, 696:417-419.

Sackstein R.  Physiologic migration of lymphocytes to lymph nodes following bone marrow transplantation:  Role in immune recovery.  Sem. in Oncology 1993, 20(5, Supp. 6):34-39.

Chin YH, Sackstein R, Cai JP.  Lymphocyte homing receptors and preferential migration pathways.  Proc. Soc. Exp. Biol. and Med. 1991: 196:374-380.

Chin YH, Falanga V, Cai JP, Sackstein R.  Molecular mechanisms mediating leukocyte migration to skin.  In:  Advances in gene technology: the molecular biology of immune diseases, IRL Press, OxfordU.K., 1990, pp. 170-73.

Chin YH, Falanga V, Streilein JW, Sackstein R.  Lymphocyte recognition of psoriatic endothelium: evidence for a tissue-specific receptor/ligand interaction.  J. Invest Dermatol. 1989; 93:82-87.

Sackstein R, Chin YH.  Mechanisms of lymphocyte migration to lymphoid tissues and inflammatory sites.  Clinical Immunology Newsletter 1988, 9:181-184.

Sackstein R, Falanga V, Streilein JW, Chin YH.  Lymphocyte adhesion to psoriatic dermal endothelium is mediated by a tissue-specific receptor/ligand interaction.  J. Invest Dermatol. 1988; 91:423-430.

Chin YH, Falanga V, Streilein JW, Sackstein R.  Specific lymphocyte-endothelial cell interactions regulate migration into lymph nodes, peyer's patches and skin.  Regional Immunology 1988; 1:78-83.

Colten HR, Cole FS, Sackstein R, Auerbach HS.  Tissue and species-specific regulation of complement biosynthesis in mononuclear phagocytes.  In:  Mononuclear phagocytes, Martinus Nijhoff Publishers, The Netherlands, 1985, pp. 147-58.

Whitehead ASSackstein R.  Molecular biology of the human and mouse MHC class III genes:  Phylogenetic conservation, genetics and regulation of expression.  Immunological Reviews 1985, 87:185-208.

Sackstein R, Colten HR.  Molecular regulation of MHC class III (C4 and factor B) gene expression in mouse peritoneal macrophages.  J. Immunol. 1984; 133:1618-1626.

Chaplin DD, Sackstein R, Perlmutter DH, Weis JH, Kruse TA, Coligan J, Colten HR, Seidman JG.  Expression of hemolytically active murine fourth component of complement in transfected L cells.  Cell 1984; 37:569-576.

Sackstein R, Roos MH, Demant P, Colten HR.  Subdivision of the mouse major histocompatibility complex by identification of genomic polymorphisms of the class III genes.  Immunogenetics 1984; 20:321-330.

Sackstein R, Colten HR, Woods DE.  Phylogenetic conservation of a class III major histocompatibility complex antigen, factor B: isolation and nucleotide sequencing of mouse factor B cDNA clones.  J. Biol. Chem. 1983; 258:14693-14697.